. Cunningham's Text-book de l'anatomie. L'anatomie. 1334 L'URINO-génitales avec le système. accessoirement ductuli efferentes qui sont dérivés de les tubules de l'rrieso- nephros, et donc les canaux de Wolff ou devient le passage pour la sécrétion du testicule. Dans les cellules épithéliales grandes femelles sont trouvés dans le stroma de l'ovaire en développement, sous l'épithélium germinal, dès le trente-troisième jour. Ces ovules primitifs sont beaucoup plus nombreux que les spermatozoïdes primitive de l'homme, et une forme très caractéristique de l'élaboration d'ovaire. Au début, ils se trouvent isoler

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. Cunningham's Text-book of anatomy. Anatomy. 1334 THE URINO-GENITAL SYSTEM. secondarily with the ductuli efferentes which are derived from the tubules of the rrieso- nephros, and thus the mesonephric or Wolffian duct becomes the passage for the secretion of the testis. In the female large epithelial cells are found in the stroma of the developing ovary, beneath the germinal epithelium, as early as the thirty-third day. These primitive ova are much more numerous than the primitive sperm cells of the male, and form a very characteristic feature of the developing ovary. At first they lie isolated, but later—about the fifthvweek—they become surrounded by other smaller cells having a like origin from the germinal epithelium. Each primitive ovum surrounded by its cells becomes a primitive follicle, the further development of which has already been described (p. 1318). During the later stages the epi- thelium has the appearance of growing down into the stroma in the form of long branching cellular processes which break up into little nests of cells to form the future follicles (p. 1318). The proliferation of cells from the surface epithelium goes on until the seventh month, but it is extremely doubtful if any new ova arise in the later months of gestation or after birth.. The Generative Ducts. Fig. 1045.—The Urino-genital Passages at the Indifferent Stage of Development. Ureter, green solid outline. Wolffian duct, green dotted outline. The origin of the vesicula seminalis is indicated. Miillerian ducts, orange. Rectum, bladder, and urino-genital canal, red. Generative DuCtS.—As has been already stated, the male ducts arise from the Wolffian, and the female from the Miillerian ducts of the embryo. Both sexes at first possess well-developed Wolffian and Miillerian ducts, which are arranged in a very definite manner. The Wolffian ducts communicating directly with the tubules of the mesonephros lie at first parallel to, and at a considerable distance from one another.

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