Des études en pathologie cardiaque . ment dans le septum ventriculorumcontinuous avec celui observé dans le ventricule droit. Sur le côté gauche l'ouverture mesure 2,5 x 1,5 cm.Il est presque fermée, cependant, par l'importante végétation découlant de ses marges. L'endo-canliimi du ventricule gauche s'étend dans l'ouverture et n'est apparemment que theriijlil luith continue d rriilnrlr. La direction de l'adoption entre les ventricules est à la baisse et backwardfrom la gauche vers le côté droit. L'anneau aortique mesures 6 cm. de circonférence. Toutes les vannes d'theaortic sont beaucoup épaissi et quelque peu cont

• Contributeur: The Reading Room / Alamy Banque D'Images
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Studies in cardiac pathology . ening in the septum ventriculorumcontinuous with that seen in the right ventricle. On the left side the opening measures 2.5 x 1.5 cm.It is almost closed, however, by the extensive vegetations springing from its margins. The endo-canliimi of the left ventricle extends into the opening and is apparently continuous luith that of theriijlil rriilnrlr. The direction of the passage between the ventricles is downward and backwardfrom the left to the right side. The aortic ring measures 6 cm. in circumference. All of theaortic valves are much thickened and somewhat contracted. On the anterior and right pos-terior leaflets there are small verrucose vegetations; on the left posterior leaflet there is an enor-mous, irregularly round, nodular vegetation measuring 2.5 x 2.3 x l.S cm. in diameter. Thevegetation is attached to the entire ventricular aspect of the leaflet, and extends downward into theopening in the septum ventriculorum, nearly closing the same. No bacteriologic examinationwas made.. Kjc;. 70. 212 STUDIES IN CARDIAC PATHOLOGY TRANSPOSITION OF THE GREAT VESSELS Transposition of the great vessels is generally associated witha transposition of the other viscera. It is ascribed to non-rotationof the aortic septum from which these vessels are formed, and itis often accompanied b} patency of the foramen ovale, interven-tricular septum, or ductus arteriosus. In typical cases the aorta is in front and to the right, the pulmonary arterybehind and to the left. At one stage in the normal process both vessels areconnected with the right ventricle, the change of the aorta to the left beinglargely accomplished by the completion of the interventricular septum. Irregu-larities in the formation of this septum, especially its deviation to the right orleft, may result in both vessels arising from one or other of the ventricles, moreoften the right, an anomaly not exceedingly rare. Transposition of the vesselsmay be accompanied by transposition of the a

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