Image d'archive à partir de la page 108 de la cyclopaedia de l'anatomie et. La cyclopaedia de l'anatomie et physiologie cyclopdiaofana05todd Année : 1859 Formation de l'ovule de l'ovaire dans la grenouille. A et B. représentations grossie d'un follicule ovarien et son contenu dans un stade précoce de la formation de l'ovule. Le follicule est TL' de diamètre : dans une membrane folliculaire et sa doublure épithéliale sont principalement mis en évidence ; en B les parties de l'ovule à l'intérieur sont présentés lorsque le microscope a été réglée de manière à les placer dans l'accent. Le mur de la follicule ovarien est composée d'un sans structure

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Archive image from page 108 of The cyclopædia of anatomy and. The cyclopædia of anatomy and physiology cyclopdiaofana05todd Year: 1859 Formation of the ovarian ovum in the Frog. A, and B. Magnified representations of an ovarian follicle and its contents in an early stage of the formation of the ovum. The follicle is TL' in diameter: in A the follicular membrane and its epithelial lining are chiefly brought into focus; in B the parts of the ovum within are represented when the microscope was adjusted so as to place them in focus. The wall of the ovarian follicle con- sists of a structureless membrane or ovicapsule, and an external covering of thin flattened cells; the epithelial cells of the follicle within are seen in pro- file towards the margin, and full towards the centre (in A) where their granular contents and nuclei are distinct. In the centre of B the large germinal vesi- cle with numerous macula? is seen ; around it a clear space which is a part of the basement substance of the primitive yolk, and between this and the wall of the follicle there is seen superiorly the dark granular mass which has been called yolk nucleus. The clear primitive yolk is also surrounded by a finely granu- lar vitelline substance which has begun to be de- posited. line of the clear part remains remarkably smooth and well-defined for a time, and there appears to be some fluid or different substance interposed between it and the inner surface of the ovicapsule. The homoge- neous membrane of the latter is found at an earlv period to be lined by a single layer of very distinct largely nucleated cells, which lie flatly applied against its inner surface, but bulge or project roundly on their other sides towards the ovum. This layer of cells no doubt cor- responds to the tunica granulosa of the ovisac in other animals, and has a similar destina- tion. There is as yet, neither in the earlier ova nor in those half-grown, any zona or other proper vitelline membrane; and it is obvious tha

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