. Le manuel de référence des maladies de la peau. L'affection, comme il est rare de le meetwith parmi les bien-à-faire. Il y a peu de doute que la maladie est contagieuse. Bien que l'inoculation-expérimententshave ait échoué dans la plupart des cas, il y a encore quelques MOLLUSUM COXTAGIOSTJM. 347 cas dans lesquels ils ont réussi. Au printemps de 1891, un enfant atteint de mollusques contagiosum est entré dans myservice à l'hôpital de l'île Randalls, et en quelques semaines, aucune tentative n'a été faite pour détruire les tumeurs, les cas de thereweresix dans les quartiers. Pathologie. La véritable anatomie pathologique des theségrowths a

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. The ready-reference handbook of diseases of the skin. the affection, as it is rare to meetwith it among the well-to-do. There is little doubt thatthe disease is contagious. Though inoculation-experimentshave failed in most instances, still there have been a few MOLLUSCUM COXTAGIOSTJM. 347 cases in which they have been successful. In the spring of1891 a child with molluscum contagiosum came into myservice in Randalls Island Hospital, and within a few weeks, no attempt being made to destroy the tumors, thereweresix cases in the wards. Pathology. The true pathological anatomy of thesegrowths has not been settled, but the old idea that theyspring from the sebaceous glands is no longer entertained.The rete seems to be the starting-point of the disease. Oneof the most characteristic features of the disease is theso-called molluscum corpuscle, which is but a changedepithelial cell (Fig. 41). These appear, under the micro-scope, as large, ovoid, lustrous bodies, without nuclei, somebeing either wholly or partly contained in an epidermic Fig. 41.. [Molluscum corpuscles. (After Kaposi.) envelope, and some being entirely uncovered. Severalparasites have been declared to be the cause of the diseaseby different investigators, the latest candidates being thepsorosperm of Darier in 1889, and the gregarine of Neisserin 1888. Torok1 declares these to be merely artificialproducts of the methods used, and is sure that the diseaseis not due to a parasite. Diagnosis. The appearance of the disease is so charac-teristic as to be diagnostic. It is most apt to be confusedwith milium, but if it is remembered that a milium has nocentral depression, while a molluscum has, the confusion will 1 Monatshefte f. prakl. Dermat., 1890, x. 149. 348 DISEASES OF THE SKIN. exist no longer. If they are taken for the vesico-pustules ofvariola, a scarcely probable occurrence, pricking their topswill at once show that they are not pustules, and if they arewatched for a day or so it will be found that they re

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