. Les effets de l'inanition et de la malnutrition sur la croissance et la structure. La famine ; la nutrition. 296 INANITION ET DE LA MALNUTRITION dans l'aspect plus sombre de la moelle. La formation de globules rouges à partir de l'HassaH cellules épithélioïdes continue. À 4 jours, "delymphoidisation" est complète et qu'il n'est mais légère distinction entre cortex et médullaire. Mitoses ont entièrement disparu ; les corpuscules de Hassall devenir fibrose et sont détruits par les eosinophiles. Récupération de la réalimentation sur rat est impossible à ce stade, mais se produit après 2 jours de jeûne. Le processus de "relymphoidisation"

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. The effects of inanition and malnutrition upon growth and structure. Starvation; Nutrition. 296 INANITION AND MALNUTRITION medulla darker in appearance. The formation of HassaH's corpuscles from the epithelioid cells continues. At 4 days, "delymphoidisation" is complete and there is but slight distinction between cortex and medulla. Mitoses have entirely disappeared; Hassall's corpuscles become cystic and are destroyed by eosinophiles. Recovery of the rat upon refeeding is impossible at this stage, but occurs after 2 days of starvation. The process of "relymphoidisation" is somewhat slow, mitoses appearing rare after 48 hours of refeeding. At least a week is required to re-establish the normal lymphoid structure. A chick. Fig. 80. Fig. 81. Fig. 80.—Photograph of a cross section of the thymus in a normal albino rat (S. 2) at 3 weeks of age. The gland is mostly cortex, the few light areas representing the medulla. The capsule and interlobular septa are thin. A, perithymic adipose tissue. Zenker fixation; alum-hematoxylin stain. X22. Fig. 81.—Photograph of a cross section of the thymus in an albino rat (S. 11) held at constant body weight by underfeeding from 3 to 10 weeks of age. The thymus is greatly reduced in size, and the distinction between cortex and medulla obliterated. The capsule and interlobular septa are relatively thickened. Some masses of atrophic, perithymic adipose tissue (A) are included in the section. Zenker fixation; alum-hematoxylin stain. X22. (a few days old) after 12 hours' starvation showed beginning "delymphoidisa- tion, " similar to that in mammals. Lizards starved 1-5 weeks also showed the typical thymic involution, but a teleost fish ("Chat de Mer") showed no appreciable change in 6 days. Some of the changes observed in the weight of the thymus of the albino rat during inanition by Jackson and his co-workers are shown in Table 4. In rats underfed from the age of 3 weeks to 10 weeks, Jackson ('15a

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