. Pathologie gynécologique ; un manuel de technique microscopique et au diagnostic dans la pratique gynécologique, pour les étudiants et les médecins. fdl d2,) à nouveau des groupes isolés de cellules whi-ahare marqué fortement du petit-aresmaller tétracellulaires l'infiltration ; ces nids de cancer. Il peut être vu, par conséquent, que l'ensemble de l'isquite tissu changé en caractère. Des constituants normaux du carcinome du col de l'utérus. Tissu 65 aucun n'est présent dans la section, et nous ne devons pas hésiter à diagnosea carcinome avec certitude à partir de Sucha photo seul. Si nous étudions plus thespecimen (bien que cela ne peut pas être

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. Gynecological pathology; a manual of microscopic technique and diagnosis in gynecological practice, for students and physicians. dlf d2, ) again isolated groups of cells whi-ahare sharply marked off from the small-celled infiltration; these aresmaller cancer nests. It may be seen, therefore, that the entire tissue isquite changed in character. Of the normal constituents of the cervical CARCINOMA OF THE CERVIX. 65 tissue none is present in the section, and we need not hesitate to diagnosea carcinoma with certainty from sucha picture alone. If we study thespecimen further (though this cannot be illustrated in a drawing) wefind that such cell nests infiltrate the remaining cervical tissue, and thatthe small-celled infiltration extends still further into the deeply situatedparts. In this specimen nothing can be seen of the connective-tissuegroundwork, since everything is covered by the enormous small-celledinfiltration. This is, however, as already mentioned, characteristic ofthe reaction of tissue to a neoplasm in the early stages. If the processhad existed a longer time we should have found more fibrous connective. Figure 23.—Gland whose Wall at one side is Destroyed by Carcinomatous Changes.a, dark round structures : b, normal epithelia which have retracted from the surround-ing tissue; c, carcinoma which has, on the right, broken through the wall. tissue in place of the exclusive small-celled infiltration. Such typicalpictures of carcinoma are already well known from the text books ongeneral pathology. Therefore I have given in Fig. 21 a view rarelyseen in schematic drawings, but one which is often met with in micro-scopical sections. Fig. 22 serves as a general view with a lower power. It shows by low power how the cervix is for the most part destroyedby the neoplasm; perhaps the connective-tissue groundwork may be con-sidered the remains of the stroma of the vaginal portion of the cervix. In the same way a carcinoma originating in the cervical canal is to be ju

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