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Produced by the National Institute of Allergy and Infectious Diseases (NIAID), this scanning electron micrograph (SEM) depicts a clump of spheroid-shaped Staphylococcus aureus bacteria that were enmeshed in filamentous extracellular matrix, which normally binds cells together within the body's various tissue types. One form of Staphylococcus aureus bacteria known as methicillin-resistant Staphylococcus aureus, or MRSA, causes a range of illnesses, from skin and wound infections to pneumonia and bloodstream infections that can cause sepsis and death. Staph bacteria, including MRSA, are one of the most common causes of healthcare-associated infections. Resistance to methicillin and related antibiotics (e.g., nafcillin, oxacillin) and resistance to cephalosporins are of concern. CDC estimates 80, 461 invasive MRSA infections and 11, 285 related deaths occurred in 2011. An unknown but much higher number of less severe infections occurred in both the community and in healthcare settings.