. The Journal of Laboratory and Clinical Medicine . rt montrant 378 LE JOURXAL DE LABORATOIRE ET CLINIQUE ilEDICIXE l'effet de stimuler les nerfs extrinsèques à l'estomac, et surtout tole sphincter pylorique sont extrêmement rares dans la littérature. MÉTHODES EXPÉRIMENTALES nos expériences ont été réalisées sur des chiens. Dans les 171 stimulations sveredone sur 36 animaux. L'anesthésie à l'éther a été utilisée pour toutes les procédures opératoires.dans la plupart des cas, l'éther a été utilisé tout au long de l'expérience. Dans certains cas, la casémorphine a été utilisée en plus de l'éther et, dans certaines expériences, la morphinealone a été utilisée après l'opér

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. The Journal of laboratory and clinical medicine . rt showing 378 THE JOURXAL OF LABORATORY AND CLINICAL ilEDICIXE the effect of stimulating the extrinsic nerves to the stomach, and especially tothe pyloric sphincter are extremely rare in the literature. EXPERIMENTAL METHODS Our experiments were performed on dogs. In all 171 stimulations sveredone on 36 animals. Ether anesthesia was used for all operative procedures.In most cases ether was used throughout the experiment. In some casesmorphine was used in addition to ether and in certain experiments morphinealone was relied upon after the operations were completed. The three methodsof anesthesia gave similar results but the most satisfactory from every pointof view was ether with a small dose of morphine. The method of obtaining graphic records of the movements of the parspylorica and duodenum has been described in detail in previous publica-tions.^ ^ ^^ When the sphincter alone was to be studied a specially con-structed balloon consisting of a finger cot stretched over two hard rubber. Fig. 1.—Diagram of apparatus; A, modified balloon or pylorograph; B, triple chambered balloon ortriple enterogram used to record simultaneously contractions of the pyloric sphincter, antrum, and duo-denum. cones (Pig. lA) was placed in the pyloric canal through an opening in thefundie end of the stomach and secured in place by sutures through the gastricand duodenal walls. When the pylorus antrum and first part of the duodenumwere also to be studied a balloon divided into three parts was secured inposition and a tube led from each portion so that simultaneous records couldbe made of antral, sphincteric, and duodenal contractions (Fig. IB). Pressurewas maintained in these balloons by means of a water manometer connectedto each. Pressures in the chambers were varied according to our judgmentof the tonus of the structures concerned. As a rule a slightly higher pressurewas needed in the pyloric balloon than in the others. Pressures nea

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