Un système de médecine, par de nombreux écrivains ; . n'est que rarement que le nerf olfactif isaffected ; Pierrot a décrit l'atrophie du nerf dans un cas d'tabesin où il y avait ])ccn anosmie. Des anomalies visuelles et la cécité ne sont pas atall rare, et ceux-ci sont dus à un gris dégénérescence du nerf optique.La couche de cellules ganglionnaires de la rétine correspond au nerf-cellules du TABES SOR A US 105 ganglions spinaux ; d'abord le nerf-fi])res du nerf optique sont touchés, andsooner ou plus tard les cellules de la rétine (aussi Alobius). Alsospreads centrahvards le processus vers l'corpora quadrigemina et je

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A system of medicine, by many writers; . is seldom that the olfactory nerve isaffected ; Pierrot has described atrophy of the nerve in a case of tabesin which there had ])ccn anosmia. Visual defects and blindness are not atall uncommon, and these are due to a gray degeneration of the optic nerve.The ganglion cell layer of the retina corresponds to the nerve-cells of the TABES DORS A US 105 spinal ganglia; first the nerve-fi])res of the optic nerve are affected, andsooner or later the cells of the retina also (Alobius). The process alsospreads centrahvards towards the corpora quadrigemina and internalgeniculate bodies. The permanent ocular palsies are occasioned by adegeneration of the oculo-motor nerve nuclei. The fine fibres betweenthe cells in the nuclei are atrophied; the cells themselves are shrunkenand pigmented and partly destroyed. With the degeneration of thenuclei we find degeneration of the root fibres and of the peripheral nervesof the eye muscles. In some cases these are affected alone, the nucleibeing unchanged.. Fio. 3.—Photomicrograph of a section of the spinal cord at the level of the Sth cervical from a case oftabetic general paralysis. There is advanced sclerosis of the posterior columns. The comu com-missural fibres of Westphal, endogenous in origin, are seen to be undegenerated. The ascending root of the fifth, the fibres of which spring from theGasserian ganglion, has been found sclerosed in a case in which there weresymptoms during life pointing to affection of the fifth (Oppenheim). Like-wise the solitary bundle Avhich consists of afferent vagus and glosso-pharyngeal fibres was found sclerosed. I have found partial sclerosis ofthis bundle in a case of cerebro-bulbar tabes in which during life therewas loss of taste. Deafness observed during life has been found afterdeath to be due to atrophy of the auditory nerve. Besides the oculo-motor nuclei, another purely motor group of nerve-cells may be atrophied, namely, the hypoglossal; and hemiatrop

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