. Microörganismes pathogènes; un manuel pratique pour les étudiants, les médecins et les agents de santé . virulent plus long (cinq à huit jours). Chauffé pendant cinq minutes à 55° C.it devient non virulent. 5. La piqûre d'un moustique infecté ne devient infectiousque douze jours (à une température de 31 °C) après avoir mordu le premier patient. La cause de la maladie reste encore non découverte, sans normesbeaucoup d'étude du sang humain et d'autres tissus et des mos-quitoes infectés. Les filtrats de sang infectieux ne montrent rien avec l'éclairage du champ sombre, sauf les petits granules dansants semblables à TH

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. Pathogenic microörganisms; a practical manual for students, physicians, and health officers . virulent longer (five to eight days). Heated for five minutes at 55° C.it becomes non-virulent. 5. The bite of an infected mosquito does not become infectiousuntil twelve days (at a temperature of 31° C.) after it has bitten thefirst patient. The cause of the disease still remains undiscovered, notwithstandingmuch study of human blood and other tissues and of infected mos-quitoes. The infective blood filtrates show nothing with the dark-field illumination except small dancing granules similar to those foundin healthy persons. 580 RABIES—YELLOW FEVER Certain facts relating to the disease seem to point to protozoa asthe cause; for instance, the necessity for a second host and the longincubation time required before that host becomes infective afterbiting a yellow-fever patient. The bodies described by Seidelm under the name paraplasma have , been shown by Agramonte to be tissue changes. The higher monkeys seem to be susceptible, though no completeexperiments have been made with them.. Fig. 198.—The yellow-fever mosquito (Aedes calopus). Adult female. (Howard.) Much enlarged. The Yellow-fever Mosquito (Figs. 198-203).—The name Stegomyiafor this small tropical mosquito was suggested by the English entomol-ogist Theobald, who separated this genus from the genus Culex, withwhich it was formerly classed. It was first given the specific nameFasciata, but Blanchard proved that this had already been used and thename Calopus (Meigen, 1818) was found to be the proper one. Later thegenus Stegomyia was shown to be invalid and the organism now goesby the name Aedes calopus Meigen. Salient characteristics of Aedesare: (1) The palpi in the male are as long or nearly as long, as theproboscis; in the female the palpi are uniformly less than one-half YELLOW FEVER 581

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